Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo

Abstract

The use of biomaterials in dental surgery has become an important area of research. This material can be used for the purpose of filling defects, replace portions bone, bone augmentation, facilitate or enhance the repair of bone defects by bone conduction, providing mechanical support to the membrane and stabilize the blood clot .The geometry of these biomaterials to promote invagination of blood vessels. For this, it needs to be porous and have interconnected macropores. The surface of bone substitutes are determined by their chemical composition, microporosity, surface roughness, crystallinity and crystal size.This study presents the results of histomorphometric use of three commercially available substitutes. The model of defects in the calvaria of rabbits used is well established in the literature, with consistent results. In this case, both the defects filled with the biomaterials showed better distribution in the newly formed bone , lower volume loss and reduced migration into the soft tissue defect , then the conclusion is that both bone substitutes showed used biocompatibility , not negatively affect the repair process. However, the synthetic biomaterial NanoSynt had higher levels of bone formation and maintenance of the defect when compared to materials BoneCeramic ® and Bio-Oss ® during the two periods in vivo in the present study (4 and 8 weeks).