Avaliar clinicamente uma solução contendo 0,12% de clorexidina, 0,05% de cetilpiridínico, e 0,05% de fluoreto de sódio na formação da placa e manchamento dental

Abstract

Despite it ́s efficacy in treating oral infections, dental and tongue staining

associated with the use of chlorhexidine is one of the adverse which discourages it ́s

long-term use the most. The aim of this study was to analyze the effect of a solution

containing 0,12% chlorhexidine , 0,05% cetylpyridinium and 0,05% sodium fluoride

on the anti-plaque activity and extrinsic dental and tongue staining. 48 dental

students volunteered for the study, with a mean of 22,3 years of age. The design of

the study was double-blind, randomized, placebo-controlled. The participants were

allocated in 3 groups, and received the following solutions: Group I - solution

containing 0,12% chlorhexidine , 0,05% cetylpyridinium and 0,05% sodium fluoride (

Noplak Max ®

solution. In the 1st phase of the study the individuals were instructed to quit al oral

hygiene measures for 24h, after receiving a prophylaxis and using 15ml of the

allocated mouthwash for 1 min. After this period, the individuals had their teeth

photographed with a digital camera, so that the area covered with plaque and

evidenced with fucsine could be analyzed. During the 2nd phase , after a 1 week

interval, the participants received another prophylaxis and the oral hygiene methods

were quit for 3 days. During this period the volunteers were instructed to use the

allocated mouthwash, under supervision, 8 times a day, for 1 min. Immediately after

the volunteers also drank warm black tea (35°C) for 2 min. The area and intensity of

the staining of the teeth and tongue were analyzed with the means of digital

photography using an image editor software. The results of inhibitory plaque

formation activity showed a difference in plaque covered area approximately 25%

less in Group I and II than in Group III. Group I showed a higher number of areas free

of staining, and a lower number of areas with light or moderate staining, when

compared with the other groups ( p<0,05). Also the number of individuals with

); Group II – solution of chlorhexidine 0,12%; Group III – Placebo

moderate, or moderate/intense staining, was smaller in Group I when compared with

the other groups ( p< 0,05). None of the individuals in Group I showed intense dental

or tongue staining, whereas 25% ( 4/16) of the individuals of Group II showed this

type of dental staining, and 6% (1/16) of intense tongue staining. The results of this

study showed that the tested solution ( Noplak Max ®

formation inhibition, showing a higher percentage of staining-free surfaces, and a

lower staining potential than the other solutions.